Usually , clr is binding to c1inh ( cl inhibitor ) . when immune complex ( ic ) binds to clq , c1inh is detached form clr , and then the serine protease is activated , and then the complement classical pathway is activated 在一般情況下, c1r與c1inh ( c1inhibitor )結(jié)合著,而一旦有免疫復(fù)合物( ic )結(jié)合到c1q上時(shí),浙江大學(xué)碩士學(xué)位論文cllnh的抑制作用即行移除, clr的構(gòu)象發(fā)生改變,具有酶活性,從而啟動(dòng)補(bǔ)體激活經(jīng)典途徑。